2U server with AMD EPYC CPU, 8 DIMMs, 4 NVMe, 8 GPUs, 11 PCIe 4.0, and dual GbE


  • AMD EPYC™ 7002 & 7003 Series processor with 64 cores/128 threads (280W)
  • Up to 11x PCIe® 4.0 slots
  • 4x double-slot or 8x single-slot GPUs, including NVIDIA® A100, Tesla® T4 or Quadro®
  • A Xilinx Alveo-qualified server support for Alveo U50 to provide optimized acceleration
  • Supports NVIDIA® NVLink bridge to enable scaling of visual computing workloads
  • A choice of PCIe Gen 4.0, OCP 3.0, NVMe and M.2 on the front panel
  • Redundant 2200W or 1600W Platinum power supplies
  • 2x hot-plug, hot-swap fans design
  • Remote management

ESC4000A-E10 is a single-socket GPU server satisfies most of your workload needs, helping you reduce cooling expenses and licenses.

Powered by AMD EPYC™ 7003 & 7002 series processors
The AMD EPYC™ 7003 & 7002 processor features the world's first 7nm datacenter-design and a PCI Express® 4.0-capable x86 server processor with up to 2X the performance and 4X the floating-point capability. With support for up to 64 cores, 128 threads, 8-channel DDR4 3200, 128 PCIe 4.0 lanes and up to 280 watts of max. thermal design power (TDP), this processor also includes memory and virtualization encryption features to ensure exceptional security.

Flexible Design and Performance
- Flexible front panel design that allows for easy storage and network expansions and upgrades. The design offers easier accessibility of up to 4x NVMe SSD drives and an optional choice of OCP 3.0, a hyper M.2 adapter or HBA/RAID card via PCIe 4.0 slot for better performance and lower latency.
- Supports up to 4x PCIe Gen 4.0 double-deck GPUs/ Full length cards or 8x PCIe Gen 4 single-wide GPUs and 3x PCIe Gen4 slots for increased acceleration.

Multi-GPU support
ESC4000A-E10 features a powerful GPU architecture that supports up to four double-slot or eight single-slot GPUs in a 2U chassis, including NVIDIA® A100, Tesla® or Quadro®, plus features NVIDIA NVLink® Bridge to enable scaling of performance in order to meet the demands of AI and high-performance computing, and to securely run workloads in virtualization environments. ESC4000A-E10 is also a Xilinx Alveo-qualified server to provide optimized acceleration for workloads across cloud and on-premises data centers, and for hybrid cloud environments in financial computing, machine learning, computational storage, and data search and analytics.

ESC4000A-E10 is a NVIDIA RTX server validate system that deliver unprecedented performance at a fraction of the cost, space, and power requirements of traditional CPU-based solutions, from production rendering to scalable visualization systems or HPC, AI, ML, big data analytics, and at the edge deployment options.

Ultrafast connectivity for HPC applications
ESC4000A-E10 features a OCP 3.0 mezzanine card to deliver speeds of up to 200 Gbps for HPC applications that require high-bandwidth, low-latency network support for connecting multiple nodes and clusters.

Scalable storage design
To effectively manage the storage demands of growing amounts of data, ESC4000A-E10 has a dense chassis design that accommodates up to eight 3.5-inch or 2.5- inch drives, including up to four NVMe SSDs support. One onboard 22110-length M.2 SSD allows faster data transfer speeds for OS installation, and a hyper M.2 card is available to provide even greater expansion capability.

Performance Boost technology
This technology improves workload throughput by maximizing processor frequency and boost power, ideal for time-sensitive applications such as financial services or data center operations. In the BIOS you can choose from pre-configured server profiles optimized for specific workloads, maximizing overall performance and reducing server-configuration time.

Processor / System Bus1 x Socket SP3 (LGA 4094)
AMD EPYC™ 7002 & 7003 Series Processors Support (up to 280W)
Memory- Total Slots : 8 (8-channel)
- Capacity : Maximum up to 2048GB RDIMM
- Memory Type :
- Memory Size :
256GB, 128GB, 64GB, 32GB, 16GB
Expansion SlotsRear:
- 4 x PCIe x16 slots (Gen4 x16 link, FH,FL) for dual-slot GPU cards or
8 x PCIe x16 slots (Gen4 x8 link, FH,FL) for single-slot GPU cards
- 2 x PCIe x16 slots (Gen4 x16 link, LP,HL)

- SKU-1 (default)
 1 x PCIe x8 slot (Gen4 x8 link, LP,HL)
- SKU-2 (by request)
 1 x PCIe x8 slot (Gen4 x8 link, LP,HL) or
 1 x OCP3.0 slot (Gen4 x8 link) by switching cables
- SKU-3 (by request)
 1 x PCIe x8 slot (Gen4 x8 link, LP,HL) or
 2 x M.2 socket (Gen4 x4 link, up to 22110 module) by switching cables
- Storage Controller :
CPU Integrated
- Optional kits Controller :
ASUS PIKE II 3008-8i 8-port SAS 12G RAID card
ASUS PIKE II 3108-8i 8-port SAS 12G HW RAID card
Drive Bays8 x 3.5" or 2.5" Hot-swap Storage Bays
(Backplane Supports 4 x SATA/SAS + 4 x SATA/SAS/NVMe Devices)

1 x M.2 socket (Gen4 x4 link, up to 22110 on-motherboard)
Networking2 x Gigabit LAN ports (Intel® I350-AM2)
1 x dedicated Mgmt LAN port (BMC AST2500)
SecurityTPM2.0 Support
Front I/O Ports1 x Q-code/port-80 LED
4 x USB 3.2 Gen1 ports
Rear I/O Ports2 x USB 3.2 Gen1 ports
2 x Gigabit LAN ports (RJ45)
1 x Management port (RJ45)
1 x VGA port
Switch/LEDFront :
1 x Power Button/LED
1 x Location Button/LED
1 x Message LED
1 x HDD Access LED
1 x Q-Code/Port 80 LED
Rear :
1 x Power Button/LED
1 x Location LED
1 x Message LED
1 x HDD Access LED
Management SolutionASUS Control Center Enterprise (in-band)
ASMB9-iKVM for KVM-over-IP (out-of-band/BMC AST2500)
Regulatory ComplianceBSMI, CE, RCM, FCC (Class A)
Dimensions800mm x 440mm x 88mm (2U)
31.50" x 17.22" x 3.46"
Form Factor2U
WeightNet Weight: 34 Kg
Gross Weight: 44 Kg
Power Supply1+1 Redundant 1600W 80 PLUS Platinum Power Supply
Rating: 100-127Vac/200-240Vac,12.9A/9.5A,50-60Hz

1+1 Redundant 2200W 80 PLUS Platinum Power Supply
Rating: 100-127Vac/200-240Vac,14A/12.6A,47-63Hz
EnvironmentOperation temperature: 10℃ ~ 35℃ / Non operation temperature: -40℃ ~ 70℃
Non operation humidity: 20% ~ 90% ( Non condensing)
Note*Users need to remove Slimline cables from the PCIe riser board, and re-connect the cables to the backplane for total 4 x NVMe devices support.

Ordering Guide
ESC4000A-E10 2U server with AMD EPYC CPU, 8 DIMMs, 4 NVMe, 8 GPUs, 11 PCIe 4.0, and dual GbE

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